Carlito Brigante is released from jail after serving five years of a much longer stretch. He vows to go straight and to live life as a fine, upstanding citizen. He even rekindles a romance with his ex-lover. However, Carlito’s associates cannot seem to leave him in peace…his nephew involves him a pool-room gunfight, his lawyer asks him for “favours” which spiral out of control, and even an old friend (now a wheelchair bound paraplegic) tries to get him into trouble with the law. Carlito decides to make a run for Florida and the promise of a new life, but has one final dramatic escape to make from some hoods who believe (wrongly) that he was behind the murder of their boss.

After auditions, 12 young dancers make it to the American Ballet Academy. They’ll prepare for the student showcase to determine who will be asked to join the American Ballet Company. Tensions mount between Jonathan, the company’s aging choreographer, and Cooper, his best dancer, who also wants to choreograph. The brilliant Maureen seems poised for success, but she discovers that life is passing her by. Jody, whose body may be the wrong type and whose technique is ragged, elicits Cooper’s interest. The edgy, smart-mouthed Eva loves to dance but seems destined to be stuck in the back of the chorus. The showcase will decide their fates.

Tony is an uneducated Brooklyn teenager. The highlight of his week is going to the local disco, where he is the king of the dancefloor. Tony meets Stephanie at the disco and they agree to dance together in a competition. Stephanie resists Tony’s attempts to romance her, as she aspires to greater things; she is moving across the river to Manhattan. Gradually, Tony also becomes disillusioned with the life he is leading and he and Stephanie decide to help one another to start afresh.

In Chicago, the former photographer and presently advertising executive Mathew (Josh Hartnett) is closing a business deal in a fancy restaurant with a Chinese representative, when he sees a woman that looks like his former passion Lisa (Diane Kruger). Two years ago, Lisa and Matthew had a love affair, and Lisa simply vanished when Matthew invited her to move with him to New York, where he had the invitation for a better job, and Matthew is still obsessed for her. Matthew decides to follow Lisa, and when he meets her, he realizes that Lisa is indeed another woman (Rose Byrne) with the same name. Matthew stays in Chicago with his friend Luke (Matthew Lillard) and decides to investigate the mystery.