Based on Thomas Harris’ book of the same name, this prequel shows a young Hannibal Lecter in three different phases of his life from childhood in Lithuania to his ten years in England up to his time in Russia before his capture by FBI agent Will Graham in Red Dragon.

A troubled loner, Bob Maconel, imagines blowing up the tower in Los Angeles where he works. He takes a revolver to his office intent on killing colleagues, and then himself. At home, he holds conversations with his fish, who encourage him to do it. His supervisor picks on him. As he’s screwing his courage to the sticking place, he drops a bullet; while on the floor looking for it, another colleague does exactly what Bob has been planning. Bob emerges a hero and the one colleague he likes, a woman with a bright smile, is severely wounded. Can Bob help her through despair and find himself and joy in life? Or, as everyone says, is this impossible for a man like him?

In New York City, when a crime is committed, the victims are represented by two distinct yet forever intertwined forces. There’s the police department, represented here by the 27th precinct Homicide Detectives. Theres Senior Homicide Detective Cyrus Lupo and his partner Detective Kevin Bernard who both report to their boss Lieutenant Anita Van Buren. It is their job to investigate the crime, collect evidence, interview witnesses and then, when the evidence points to a suspect or suspects, place the suspect(s) under arrest. The matter is then taken over by the prosecutors of the Manhatten District Attorney’s office, Executive Assistant District Attorney Michael Cutter with support from his assistant prosecutor Connie Rubirosa who work under the watchful eye of Manhatten District Attorney John James McCoy, together they discuss deals, prepare the witnesses and evidence and conduct the people’s case in the trial. Both teams work with the Medical Examiners Office, Crime Lab and Police and District Attorney psychiatrists. Matters are rarely resolved easily, or for the people involved, satisfactorily. Crimes are committed which frequently create public unrest and controversy, race, morals and beliefs are frequently challenged and manipulated, the guilty can go unpunished and the innocent ruined forever. The detectives and prosecutors are weary, cynical, flawed, human and vulnerable. And yet they are somehow still dedicated to their jobs, to make the guilty answer for their crimes and gain some sense of justice for the victim and the victim’s family. These are their stories…

Frank Detomello catches a cold. The inside of his body is known as the “City of Frank” to its inhabitants, two of which – white blood cell cop Osmosis Jones, and cold tablet Drixorial – team up to fight the invading viruses intent on taking over the City.